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A 12-week, Open-label, Randomized, Standard of Care Controlled, Dose-ranging Safety and Efficacy Study of Dovramilast in People With Moderate to Severe Acute or Recurrent Leprosy Type 2 Reaction

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Trial Profile

A 12-week, Open-label, Randomized, Standard of Care Controlled, Dose-ranging Safety and Efficacy Study of Dovramilast in People With Moderate to Severe Acute or Recurrent Leprosy Type 2 Reaction

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 01 Jun 2026

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At a glance

  • Drugs Dovramilast (Primary) ; Prednisolone; Thalidomide
  • Indications Leprosy
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Medicines Development for Global Health

Most Recent Events

  • 26 May 2026 Planned initiation date (estimated date of first participant enrollment) changed from 1 Jan 2026 to 25 May 2026.
  • 26 May 2026 Status changed from not yet recruiting to recruiting.
  • 23 Dec 2025 Planned End Date changed from 1 Oct 2027 to 1 Dec 2027.

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