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A Randomized, Double-blind, Parallel-group Study to Compare the Pharmacokinetics, Efficacy, Pharmacodynamics, Safety, and Immunogenicity of CYB704 (Proposed Ocrelizumab Biosimilar) and Ocrevus® (EU-authorized and US-licensed) in Participants With Relapsing Multiple Sclerosis (RMS)

Trial Profile

A Randomized, Double-blind, Parallel-group Study to Compare the Pharmacokinetics, Efficacy, Pharmacodynamics, Safety, and Immunogenicity of CYB704 (Proposed Ocrelizumab Biosimilar) and Ocrevus® (EU-authorized and US-licensed) in Participants With Relapsing Multiple Sclerosis (RMS)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 14 Jul 2025

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At a glance

  • Drugs Ocrelizumab (Primary)
  • Indications Multiple sclerosis
  • Focus Pharmacokinetics; Registrational
  • Sponsors Sandoz

Most Recent Events

  • 03 Jun 2025 Planned initiation date (Estimated date of first participant enrollement) changed from 14 Apr 2025 to 15 Jun 2025.
  • 03 Jun 2025 Status changed from not yet recruiting to recruiting.
  • 06 Mar 2025 New trial record

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