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A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Monthly Subcutaneous Administration of Tonlamarsen in Participants With Uncontrolled Hypertension (KARDINAL)

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Monthly Subcutaneous Administration of Tonlamarsen in Participants With Uncontrolled Hypertension (KARDINAL)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 03 Apr 2026

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At a glance

  • Drugs Tonlamarsen (Primary)
  • Indications Hypertension
  • Focus Therapeutic Use
  • Sponsors Kardigan

Most Recent Events

  • 31 Mar 2026 Status changed from active, no longer recruiting to completed.
  • 28 Mar 2026 According to a Kardigan media release, Data from this trial were presented at the American College of Cardiologys Annual Scientific Session & Expo (ACC.26) and simultaneously published in The Journal of the American College of Cardiology (JACC).
  • 28 Mar 2026 Results presented in the Kardigan media release.

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