Trial Profile

A Phase 3 Trial to Evaluate the Long-Term Safety and Efficacy of Navenibart in Participants With Hereditary Angioedema - ORBIT-EXPANSE

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 09 Dec 2025

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At a glance

12 Nov 2025 According to an Astria Therapeutics media release, First Patient Now Enrolled in the ORBIT-EXPANSE Long-Term Extension trial.
08 Oct 2025 According to an Astria Therapeutics media release, After completing ALPHA-ORBIT, eligible participants may continue into the ORBIT-EXPANSE trial, in which all participants will receive navenibart in either Q3M or Q6M regimens.
08 Oct 2025 According to an Astria Therapeutics media release, company announced the initiation of the Phase 3 ORBIT-EXPANSE long-term trial of navenibart in people living with hereditary angioedema (HAE).

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