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A Single-arm, Phase Ib/2 Study of Nelmastobart in Combination With Trifluridine/Tipiracil and Bevacizumab in Metastatic/Recurrent Colorectal Cancer Patients With Resistance or Intolerance to Oxaliplatin and Irinotecan-based Chemotherapy

Trial Profile

A Single-arm, Phase Ib/2 Study of Nelmastobart in Combination With Trifluridine/Tipiracil and Bevacizumab in Metastatic/Recurrent Colorectal Cancer Patients With Resistance or Intolerance to Oxaliplatin and Irinotecan-based Chemotherapy

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 20 Jun 2025

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At a glance

  • Drugs Nelmastobart (Primary) ; Bevacizumab; Tipiracil/trifluridine
  • Indications Colorectal cancer
  • Focus Adverse reactions
  • Sponsors STCube Pharmaceuticals

Most Recent Events

  • 15 Jun 2025 Planned number of patients changed from 70 to 52.
  • 15 Jun 2025 Status changed from not yet recruiting to active, no longer recruiting.
  • 19 Mar 2025 New trial record

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