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Phase II, Single Arm, Multicentre Clinical Trial to Evaluate the Activity of Encorafenib Plus Binimetinib Followed by Cemiplimab And Fianlimab in Patients With BRAF Mutated Melanoma and Symptomatic Brain Metastases

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Trial Profile

Phase II, Single Arm, Multicentre Clinical Trial to Evaluate the Activity of Encorafenib Plus Binimetinib Followed by Cemiplimab And Fianlimab in Patients With BRAF Mutated Melanoma and Symptomatic Brain Metastases

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 09 Apr 2025

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At a glance

  • Drugs Binimetinib (Primary) ; Cemiplimab (Primary) ; Encorafenib (Primary) ; Fianlimab (Primary)
  • Indications Brain metastases; Malignant melanoma
  • Focus Therapeutic Use
  • Acronyms ENCEFALO

    • Most Recent Events

    • 04 Apr 2025 Planned initiation date changed from 1 Mar 2025 to 1 May 2025.
    • 25 Mar 2025 New trial record

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