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A phase 2 study of lorigerlimab as monotherapy in patients with either platinum-resistant ovarian cancer (PROC) or clear cell gynecologic cancer

Trial Profile

A phase 2 study of lorigerlimab as monotherapy in patients with either platinum-resistant ovarian cancer (PROC) or clear cell gynecologic cancer

Status: Suspended
Phase of Trial: Phase II

Latest Information Update: 05 Mar 2026

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At a glance

  • Drugs Lorigerlimab (Primary)
  • Indications Gynaecological cancer; Ovarian cancer
  • Focus Therapeutic Use
  • Acronyms LINNET

Most Recent Events

  • 24 Feb 2026 According to MacroGenics media release, company is fully committed to working closely with the FDA to resolve the partial clinical hold and we intend to resume study enrollment as soon as possible.
  • 24 Feb 2026 Status changed from recruiting to suspended.
  • 24 Feb 2026 According to MacroGenics media release, company announced that the U. S. Food and Drug Administration (FDA) has placed a partial clinical hold on its Phase 2 LINNET study. Under the partial clinical hold, no new patients will be enrolled in the LINNET study until the partial hold is lifted by the FDA. Current study participants may continue to receive study drug.

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