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Bevacizumab for the Treatment of Cerebral RAdiation Induced NecrosiS (BRAINS) Study: a Multicenter, Open-label, Randomized Clinical Trial to Assess the Clinical Efficacy and Cost-effectiveness of Bevacizumab Versus Corticosteroids As First-line Treatment in Patients with Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases

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Trial Profile

Bevacizumab for the Treatment of Cerebral RAdiation Induced NecrosiS (BRAINS) Study: a Multicenter, Open-label, Randomized Clinical Trial to Assess the Clinical Efficacy and Cost-effectiveness of Bevacizumab Versus Corticosteroids As First-line Treatment in Patients with Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 07 Apr 2025

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At a glance

  • Drugs Bevacizumab (Primary) ; Dexamethasone
  • Indications Brain disorders; Necrosis; Radiation-induced abnormalities
  • Focus Therapeutic Use
  • Acronyms BRAINS

    • Most Recent Events

    • 07 Apr 2025 Last checked against ClinicalTrials.gov: US National Institutes of Health record.
    • 25 Mar 2025 New trial record

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