Assessment of Efficacy and Safety of PD-1 Monoclonal Antibody Combined With IL-2 and CapeOX in Neoadjuvant Therapy for Locally Advanced Rectal Cancer Prior to Surgery: A Prospective, Multi-center, Randomized Controlled Study (PICM)
Latest Information Update: 06 Oct 2025
At a glance
- Drugs Tislelizumab (Primary) ; Capecitabine; Interleukin-2; Oxaliplatin
- Indications Adenocarcinoma; Rectal cancer
- Focus Therapeutic Use
Most Recent Events
- 08 Sep 2025 A new primary end-point "Clinical complete response (cCR)" is added.
- 08 Sep 2025 Planned primary completion date changed from 10 Jul 2025 to 10 Dec 2025.
- 08 Sep 2025 Status changed from not yet recruiting to recruiting.