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An Open-label, Phase 2 Pilot Study on the Efficacy and Safety of Piclidenoson in Patients With Lowe Syndrome

Trial Profile

An Open-label, Phase 2 Pilot Study on the Efficacy and Safety of Piclidenoson in Patients With Lowe Syndrome

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Feb 2026

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At a glance

  • Drugs Piclidenoson (Primary)
  • Indications Oculocerebrorenal syndrome
  • Focus Therapeutic Use
  • Acronyms PICLILOWE
  • Sponsors Can-Fite BioPharma

Most Recent Events

  • 13 Feb 2026 Status changed from planning to not yet recruiting.
  • 16 Dec 2025 According to a Can-Fite BioPharma media release, company has completed a phase II study protocol for rare genetic disease Lowe Syndrome and plans to submit it to Italian and EMA authorities in Q1 2026.
  • 14 Apr 2025 According to Can-Fite Biopharma media release, A Phase II design has been completed and preparatory work is being undertaken to initiate the study that will be conducted by Dr. Franchesca Emma from the Division of Nephrology, Bambino Gesu Children's Hospital-IRCCS Rome Italy.

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