Trial Profile

A Phase 3 Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Tobevibart+Elebsiran Combination Therapy in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide (ECLIPSE 2)

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 22 Jul 2026

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At a glance

13 Jul 2026 Status changed from recruiting to active, no longer recruiting.
16 Dec 2025 According to a Vir Biotechnology media release, clinical development costs for the ongoing trials in the ECLIPSE registrational program (ECLIPSE 1, 2 and 3) will be shared, where Norgine will contribute around 25% of go-forward external costs.
05 Nov 2025 According to Vir Biotechnology media release, topline data expected in the first quarter of 2027.

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