Trial Profile

A Phase 3 Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Tobevibart+Elebsiran Combination Therapy in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide (ECLIPSE 2)

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 29 Dec 2025

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At a glance

16 Dec 2025 According to a Vir Biotechnology media release, clinical development costs for the ongoing trials in the ECLIPSE registrational program (ECLIPSE 1, 2 and 3) will be shared, where Norgine will contribute around 25% of go-forward external costs.
05 Nov 2025 According to Vir Biotechnology media release, topline data expected in the first quarter of 2027.
07 Oct 2025 According to Vir Biotechnology media release, data from the trial will be presented at the upcoming American Association for the Study of Liver Diseases (AASLD) The Liver Meeting 2025 in Washington, D.C., November 7-11.

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