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NeoPSMA: A Phase I/II, Open-label, Multi-center Study of Neoadjuvant Treatment With [177Lu]Lu-PSMA-R2 (AAA602) and [225Ac]Ac-PSMA-R2 (AAA802) in Adults With Prostate-specific Membrane Antigen (PSMA) Positive High-risk Localized Prostate Cancer (HRLPC) Prior to Radical Prostatectomy and Pelvic Lymph Node Dissection

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NeoPSMA: A Phase I/II, Open-label, Multi-center Study of Neoadjuvant Treatment With [177Lu]Lu-PSMA-R2 (AAA602) and [225Ac]Ac-PSMA-R2 (AAA802) in Adults With Prostate-specific Membrane Antigen (PSMA) Positive High-risk Localized Prostate Cancer (HRLPC) Prior to Radical Prostatectomy and Pelvic Lymph Node Dissection

Status: Not yet recruiting
Phase of Trial: Phase I/II

Latest Information Update: 26 Mar 2025

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At a glance

  • Drugs 225Ac PSMA R2 (Primary) ; Lutetium 177 PSMA R2 (Primary) ; Fluorine 18 flotufolastat; Fluorine-18 PSMA 1007; Gallium (68Ga) gozetotide; Piflufolastat F18
  • Indications Prostate cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms NeoPSMA
  • Sponsors Novartis Pharmaceuticals

    • Most Recent Events

    • 26 Mar 2025 New trial record

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