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A Phase II, Open-label, Multi-Center, Randomized Study Comparing the Combination of Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) and Androgen Receptor Pathway Inhibitor (ARPI) vs. Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in First-line Treatment of Patients With Prostate-Specific Membrane Antigen (PSMA)-Positive Progressive Metastatic Castration Resistant Prostate Cancer (mCRPC)

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A Phase II, Open-label, Multi-Center, Randomized Study Comparing the Combination of Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) and Androgen Receptor Pathway Inhibitor (ARPI) vs. Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in First-line Treatment of Patients With Prostate-Specific Membrane Antigen (PSMA)-Positive Progressive Metastatic Castration Resistant Prostate Cancer (mCRPC)

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 07 Apr 2025

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At a glance

  • Drugs Abiraterone (Primary) ; Enzalutamide (Primary) ; Lutetium (177Lu) vipivotide tetraxetan (Primary)
  • Indications Adenocarcinoma; Prostate cancer
  • Focus Therapeutic Use
  • Acronyms PSMAndARPI
  • Sponsors Novartis Pharmaceuticals

    • Most Recent Events

    • 30 Mar 2025 Last checked against ClinicalTrials.gov: US National Institutes of Health record.
    • 28 Mar 2025 New trial record

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