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An Open-label, Phase 1 Study to Characterize the Effects of a Strong CYP3A4 Inducer on the Pharmacokinetics of MK-8527 in Healthy Adult Participants

Trial Profile

An Open-label, Phase 1 Study to Characterize the Effects of a Strong CYP3A4 Inducer on the Pharmacokinetics of MK-8527 in Healthy Adult Participants

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 08 May 2025

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At a glance

  • Drugs MK-8527 (Primary) ; Carbamazepine
  • Indications HIV-1 infections
  • Focus Pharmacokinetics
  • Sponsors Merck Sharp & Dohme

Most Recent Events

  • 29 Apr 2025 Planned End Date changed from 19 Jun 2025 to 11 Jul 2025.
  • 29 Apr 2025 Planned initiation date changed from 21 Apr 2025 to 28 Apr 2025.
  • 29 Apr 2025 Status changed from not yet recruiting to recruiting.

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