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PD-1 Antibody Plus Bevacizumab and CAPOX as First-line Treatment for Patients With RAS-mutant, Microsatellite Stable, Metastatic Colorectal Cancer: a Prospective, Open-label, Single-arm, Phase II Trial

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Trial Profile

PD-1 Antibody Plus Bevacizumab and CAPOX as First-line Treatment for Patients With RAS-mutant, Microsatellite Stable, Metastatic Colorectal Cancer: a Prospective, Open-label, Single-arm, Phase II Trial

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 31 Mar 2025

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At a glance

  • Drugs Bevacizumab (Primary) ; Capecitabine (Primary) ; Oxaliplatin (Primary) ; Sintilimab (Primary)
  • Indications Colorectal cancer; Liver metastases
  • Focus Therapeutic Use

    • Most Recent Events

    • 07 Mar 2025 Results (n=33) assessing the efficacy and safety of combining sintilimab with bevacizumab, oxaliplatin, and capecitabine as a primary therapy for patients with RAS-mutated, microsatellite stable, and mCRC were published in the BMC Cancer
    • 07 Mar 2025 New trial record

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