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A Randomized, Open-Label, Active-Controlled Study Evaluating the Efficacy of Three Times Weekly Vadadustat Compared to Standard of Care ESA in Patients With Anemia of CKD Receiving In-Center Hemodialysis

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Trial Profile

A Randomized, Open-Label, Active-Controlled Study Evaluating the Efficacy of Three Times Weekly Vadadustat Compared to Standard of Care ESA in Patients With Anemia of CKD Receiving In-Center Hemodialysis

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 05 Dec 2025

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At a glance

  • Drugs Vadadustat (Primary)
  • Indications Anaemia
  • Focus Therapeutic Use
  • Acronyms VOCAL
  • Sponsors Akebia Therapeutics

Most Recent Events

  • 10 Nov 2025 According to Akebia Therapeutics media release, trial design was presented at ASN Kidney Week
  • 20 Aug 2025 Planned number of patients changed from 500 to 350.
  • 20 Aug 2025 Planned End Date changed from 1 Apr 2026 to 1 Jun 2026.

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