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Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX-Intolerant Patients) Combined With R-CHOP and Orelabrutinib in the Treatment of Systemic DLBCL With Central Nervous System Involvement

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Trial Profile

Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX-Intolerant Patients) Combined With R-CHOP and Orelabrutinib in the Treatment of Systemic DLBCL With Central Nervous System Involvement

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 02 Apr 2025

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At a glance

  • Drugs Methotrexate (Primary) ; Orelabrutinib (Primary) ; Thiotepa (Primary) ; Cyclophosphamide; Doxorubicin; Prednisone; Rituximab; Vincristine
  • Indications CNS cancer; Diffuse large B cell lymphoma
  • Focus Therapeutic Use

    • Most Recent Events

    • 02 Apr 2025 New trial record

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