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A Randomized, Controlled, Multi-center Phase II Study of Ivonescimab (AK112) Plus Paclitaxel Versus Paclitaxel With or Without Ramucirumab as Second-line Therapy in Subjects With Advanced Gastric or Gastroesophageal Junction (G.GEJ) Cancer Who Failed Immunochemotherapy

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Trial Profile

A Randomized, Controlled, Multi-center Phase II Study of Ivonescimab (AK112) Plus Paclitaxel Versus Paclitaxel With or Without Ramucirumab as Second-line Therapy in Subjects With Advanced Gastric or Gastroesophageal Junction (G.GEJ) Cancer Who Failed Immunochemotherapy

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 12 Jun 2025

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At a glance

  • Drugs Ivonescimab (Primary) ; Paclitaxel (Primary) ; Ramucirumab
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Therapeutic Use

Most Recent Events

  • 05 Jun 2025 Planned initiation date changed from 10 May 2025 to 15 Aug 2025.
  • 04 Apr 2025 New trial record

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