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An Exploratory, Non-Interventional, Prospective, Multicenter, Nationwide, Clinical Study to Evaluate the Effects of the Complement C5 Inhibitor Ravulizumab on Serum Neurofilament Light Chain (sNfL) and Glial Fibrillary Acidic Protein (sGFAP) Levels in Patients with Aquaporin-4-Positive (AQP4-Ab+) Neuromyelitis Optica Spectrum Disorder (NMOSD)

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Trial Profile

An Exploratory, Non-Interventional, Prospective, Multicenter, Nationwide, Clinical Study to Evaluate the Effects of the Complement C5 Inhibitor Ravulizumab on Serum Neurofilament Light Chain (sNfL) and Glial Fibrillary Acidic Protein (sGFAP) Levels in Patients with Aquaporin-4-Positive (AQP4-Ab+) Neuromyelitis Optica Spectrum Disorder (NMOSD)

Status: Not yet recruiting
Phase of Trial: Phase IV

Latest Information Update: 09 Apr 2025

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At a glance

  • Drugs Ravulizumab (Primary) ; Azathioprine; Mycophenolate mofetil; Rituximab
  • Indications Neuromyelitis optica
  • Focus Pharmacodynamics

    • Most Recent Events

    • 09 Apr 2025 New trial record

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