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A Phase I/II Open-label Dose Escalation and Dose Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of AZD4360 in Adult Participants With Advanced Solid Tumours

Trial Profile

A Phase I/II Open-label Dose Escalation and Dose Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of AZD4360 in Adult Participants With Advanced Solid Tumours

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 25 Oct 2025

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At a glance

  • Drugs AZD 4360 (Primary)
  • Indications Adenocarcinoma; Biliary cancer; Carcinoma; Gastric cancer; Oesophageal cancer; Pancreatic cancer; Pancreatic ductal carcinoma; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors AstraZeneca

Most Recent Events

  • 26 Sep 2025 Planned End Date changed from 17 Nov 2027 to 16 Dec 2027.
  • 02 Jul 2025 Planned initiation date changed from 23 May 2025 to 31 Mar 2027.
  • 21 May 2025 Planned End Date changed from 14 Dec 2027 to 17 Nov 2027.

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