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An Open-label Extension Study Evaluating the Long-term Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of VX-670 in Adult Subjects With Myotonic Dystrophy Type I

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Trial Profile

An Open-label Extension Study Evaluating the Long-term Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of VX-670 in Adult Subjects With Myotonic Dystrophy Type I

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 06 Mar 2026

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At a glance

  • Drugs VX 670 (Primary)
  • Indications Myotonic dystrophy
  • Focus Adverse reactions
  • Sponsors Vertex Pharmaceuticals

Most Recent Events

  • 27 Feb 2026 Planned number of patients changed from 36 to 44.
  • 27 Feb 2026 Planned End Date changed from 24 Jul 2028 to 30 Jan 2029.
  • 27 Feb 2026 Planned primary completion date changed from 24 Jul 2028 to 30 Jan 2029.

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