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A Phase 1 Clinical Study Evaluating the safety, tolerability and pharmacokinetics of single and multiple ascending doses of PX578 in healthy adult participants

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Trial Profile

A Phase 1 Clinical Study Evaluating the safety, tolerability and pharmacokinetics of single and multiple ascending doses of PX578 in healthy adult participants

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 17 Apr 2025

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At a glance

  • Drugs Polymerase inhibitors (Primary)
  • Indications Mitochondrial disorders
  • Focus Adverse reactions; Pharmacokinetics

Most Recent Events

  • 17 Apr 2025 New trial record
  • 03 Apr 2025 According to Pretzel Therapeutics media release, the company has initiated recruitment in this study. The company has been awarded with grant from Parkinson's UK to evaluate POLG activation mechanisms in Parkinson's disease models.

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