A Multi-center, Randomized, Double-masked, Active-comparator-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
Latest Information Update: 01 May 2026
At a glance
- Drugs Ixoberogene soroparvovec (Primary) ; Aflibercept
- Indications Wet age-related macular degeneration
- Focus Registrational; Therapeutic Use
- Acronyms AQUARIUS
- Sponsors Adverum Biotechnologies
Most Recent Events
- 19 Mar 2026 Status changed from planning to recruiting.
- 12 Aug 2025 According to an Adverum Biotechnologies media release, the AQUARIUS phase 3 trial is anticipated to initiate in the fourth quarter of 2025, pending funding availability.
- 18 Apr 2025 New trial record