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A Clinical Study Evaluating PX578 for mtDNA depletion syndromes (MDDS)

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Trial Profile

A Clinical Study Evaluating PX578 for mtDNA depletion syndromes (MDDS)

Status: Planning
Phase of Trial: Phase I

Latest Information Update: 20 Apr 2025

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At a glance

  • Drugs PX 578 (Primary)
  • Indications Mitochondrial disorders
  • Focus Adverse reactions; First in man

Most Recent Events

  • 20 Apr 2025 New trial record
  • 09 Apr 2025 According to Pretzel Therapeutics media release, the company's publication of new research findings in Nature elucidating disease-modulating mechanism of action for the treatment of mitochondrial DNA (mtDNA) depletion syndromes support this recently initiated clinical study for PX578.
  • 09 Apr 2025 According to Pretzel Therapeutics media release, this first-in human clinical study has been initiated.

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