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Multi-center, Phase 1/2 Study of an Autologous Anti-CD20/BCMA CAR T Cell Therapy (C-CAR168) for the Treatment of Autoimmune Disease Refractory to Standard Therapy

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Trial Profile

Multi-center, Phase 1/2 Study of an Autologous Anti-CD20/BCMA CAR T Cell Therapy (C-CAR168) for the Treatment of Autoimmune Disease Refractory to Standard Therapy

Status: Not yet recruiting
Phase of Trial: Phase I/II

Latest Information Update: 09 Oct 2025

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At a glance

  • Drugs C CAR 168 (Primary) ; Cyclophosphamide (Primary) ; Fludarabine (Primary)
  • Indications Lupus nephritis; Proteinuria; Systemic lupus erythematosus
  • Focus Adverse reactions
  • Sponsors AbelZeta Pharma

Most Recent Events

  • 18 Sep 2025 Planned initiation date changed from 1 Jul 2025 to 1 Jan 2026.
  • 23 Apr 2025 New trial record

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