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Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer: An Open-label Randomized Controlled Phase II Study (The TOTAL Trial)

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Trial Profile

Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer: An Open-label Randomized Controlled Phase II Study (The TOTAL Trial)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 07 Aug 2025

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At a glance

  • Drugs Tislelizumab (Primary) ; Capecitabine; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Rectal cancer
  • Focus Therapeutic Use
  • Acronyms TOTAL

Most Recent Events

  • 24 Jul 2025 Status changed from not yet recruiting to recruiting.
  • 28 Apr 2025 New trial record

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