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A First-in-human, Open-label Trial to Evaluate the Combination of ACTengine® IMA203 With mRNA-4203 in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma or Synovial Sarcoma Patients (ACTengine® IMA203-102)

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Trial Profile

A First-in-human, Open-label Trial to Evaluate the Combination of ACTengine® IMA203 With mRNA-4203 in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma or Synovial Sarcoma Patients (ACTengine® IMA203-102)

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 29 Oct 2025

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At a glance

  • Drugs IMA-203 (Primary)
  • Indications Malignant melanoma; Skin cancer; Synovial sarcoma
  • Focus Adverse reactions
  • Sponsors Immatics US

Most Recent Events

  • 03 Sep 2025 Status changed from not yet recruiting to recruiting.
  • 28 Jul 2025 Planned initiation date changed from 1 May 2025 to 1 Aug 2025.
  • 06 May 2025 Planned initiation date changed from 1 Apr 2025 to 1 May 2025.

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