A multicentre, open-label, randomised, controlled non-inferiority study comparing the effect of discontinuing versus continuing methotrexate (MTX) alongside certolizumab pegol (CZP) in rheumatoid arthritis (RA)
Latest Information Update: 30 Apr 2025
At a glance
- Drugs Certolizumab pegol (Primary) ; Methotrexate
- Indications Rheumatoid arthritis
- Focus Therapeutic Use
- Acronyms PRIMERA
Most Recent Events
- 30 Apr 2025 New trial record
- 05 Apr 2025 Primary endpoint (the proportion of patients maintaining LDA without a flare (i.e., a CDAI score > 10 or intervention with rescue treatments for any reason) at week 36 (24 weeks after MTX discontinuation)), has been met, according to the results presented in the Arthritis Research and Therapy.
- 05 Apr 2025 Results presented in the Arthritis Research and Therapy.