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A Phase 1, Single Center, Open Label, Single Dose, Dose Escalation Study to Determine the Safety and Immunogenicity of a Novel Bivalent Norovirus G1.1 and G2.4 Vaccine Administered Orally to Healthy Volunteers Aged ≥ 18 Years and ≤ 80 Years Old

Trial Profile

A Phase 1, Single Center, Open Label, Single Dose, Dose Escalation Study to Determine the Safety and Immunogenicity of a Novel Bivalent Norovirus G1.1 and G2.4 Vaccine Administered Orally to Healthy Volunteers Aged ≥ 18 Years and ≤ 80 Years Old

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 25 Nov 2025

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At a glance

  • Drugs VXA G1.1 NN (Primary) ; VXA G2.4 NS (Primary)
  • Indications Norovirus infections
  • Focus Adverse reactions; Pharmacodynamics
  • Sponsors Vaxart

Most Recent Events

  • 05 May 2025 According to Vaxart Inc. media release, company remain on track to report topline data in mid-2025. The strategic partners are closely monitoring this upcoming data readout, and if the data proved thesis, it could lead to a partnership that would further advance the program.
  • 05 May 2025 New trial record
  • 29 Apr 2025 Status changed from recruiting to active, no longer recruiting.

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