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A Double-blind, Randomized, Placebo-controlled, Phase 1b Study to Assess the Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of THN391 in Early Alzheimer's Disease Subjects

Trial Profile

A Double-blind, Randomized, Placebo-controlled, Phase 1b Study to Assess the Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of THN391 in Early Alzheimer's Disease Subjects

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 20 May 2025

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At a glance

  • Drugs THN 391 (Primary)
  • Indications Alzheimer's disease
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Therini Bio

Most Recent Events

  • 14 May 2025 According to a Therini Bio media release, company announced that supported by the current data and financing, the experienced team at Therini Bio is preparing to begin dosing patients in Phase 1b trials evaluating THN391 in AD and DME.
  • 14 May 2025 According to a Therini Bio media release, company announced a $39 million extension of the Series A financing round for Therini Bio which will enable the company to advance Phase 1b studies for the treatment of Alzheimer's Disease (AD) and Diabetic Macular Edema (DME), as well as support development of a fibrin/VEGF bispecific.
  • 06 May 2025 New trial record

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