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Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Phase 1, Double-Blind, Randomized, Placebo-Controlled, Dose Escalation Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies.

Trial Profile

Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Phase 1, Double-Blind, Randomized, Placebo-Controlled, Dose Escalation Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies.

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 08 May 2025

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At a glance

  • Drugs Fostamatinib (Primary)
  • Indications Lung transplant rejection
  • Focus Adverse reactions
  • Acronyms SIMILAR

Most Recent Events

  • 07 May 2025 New trial record
  • 04 May 2025 Planned initiation date changed to 8 May 2025.
  • 02 May 2025 Planned initiation date changed from 5 May 2025 to 7 May 2025.

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