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A Multicenter, Open Phase I/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of JAB-23E73 in Patients With Advanced Solid Tumors Harboring KRAS Gene Alteration

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Trial Profile

A Multicenter, Open Phase I/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of JAB-23E73 in Patients With Advanced Solid Tumors Harboring KRAS Gene Alteration

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 29 Jan 2026

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At a glance

  • Drugs JAB 23E73 (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Jacobio Pharmaceuticals

Most Recent Events

  • 20 Jan 2026 Planned End Date changed from 31 Aug 2027 to 31 Dec 2026.
  • 25 Sep 2025 Results presented in the Jacobio Pharmaceuticals Media Release.
  • 13 May 2025 New trial record

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