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A Phase I, Multi-center, Multi-part Study to Investigate Safety, Tolerability, PK, PD, and Immunogenicity of RO7669330 Intravitreal Injections in Participants With GA Secondary to AMD: Part 1A: Open-label, MAD; Part 1B: Randomized PD Pilot; Part 2: Masked, Randomized, Active-comparator-controlled

Trial Profile

A Phase I, Multi-center, Multi-part Study to Investigate Safety, Tolerability, PK, PD, and Immunogenicity of RO7669330 Intravitreal Injections in Participants With GA Secondary to AMD: Part 1A: Open-label, MAD; Part 1B: Randomized PD Pilot; Part 2: Masked, Randomized, Active-comparator-controlled

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 28 May 2025

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At a glance

  • Drugs Avacincaptad pegol (Primary) ; Pegcetacoplan (Primary) ; RO 7669330 (Primary)
  • Indications Age-related macular degeneration; Dry macular degeneration
  • Focus Adverse reactions
  • Sponsors Roche

Most Recent Events

  • 20 May 2025 Status changed from not yet recruiting to recruiting.
  • 15 May 2025 New trial record

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