Trial Profile

A Phase 1, Open-label, Single-arm Study to Investigate the Safety, Tolerability, and Preliminary Efficacy of TNFa and IL-2 Coding Oncolytic Adenovirus TILT-123 in Combination With Lymphocyte-depleting Chemotherapy and Tumor-infiltrating Lymphocytes in Melanoma Patients.

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 16 May 2025

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At a glance

Drugs Cyclophosphamide (Primary) ; Fludarabine (Primary) ; Igrelimogene litadenorepvec (Primary)
Indications Malignant melanoma
Focus Adverse reactions
Acronyms TUNINTIL-2
Sponsors TILT Biotherapeutics

16 May 2025 New trial record
13 May 2025 According to a TILT Biotherapeutics media release, company announced that it has raised USD 25.6 million (EUR 22.6 million) in a Series B financing, will support the development of this trial.

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