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A Phase II Clinical Study to Evaluate the Efficacy and Safety of BL-B01D1 in Combination With Tyrosine Kinase Inhibitor (TKI) With or Without Pembrolizumab (BL-B01D1+TKI±Pembrolizumab) in Patients With Locally Advanced or Metastatic Renal Cancer

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Trial Profile

A Phase II Clinical Study to Evaluate the Efficacy and Safety of BL-B01D1 in Combination With Tyrosine Kinase Inhibitor (TKI) With or Without Pembrolizumab (BL-B01D1+TKI±Pembrolizumab) in Patients With Locally Advanced or Metastatic Renal Cancer

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Nov 2025

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At a glance

  • Drugs Izalontamab brengitecan (Primary) ; Pembrolizumab (Primary) ; Axitinib; Lenvatinib
  • Indications Renal cancer; Renal cell carcinoma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Sichuan Baili Pharmaceutical

Most Recent Events

  • 17 Nov 2025 Protocol amended with addition of Lenvatinib
  • 17 Nov 2025 Planned number of patients changed from 120 to 260.
  • 27 Aug 2025 Status changed from not yet recruiting to recruiting.

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