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A Phase 1 Study to Further Investigate the Pharmacokinetics, Safety and Tolerability, Food Effect and Drug-Drug Interaction of LY4268989 (MORF-057) in Healthy Participants

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Trial Profile

A Phase 1 Study to Further Investigate the Pharmacokinetics, Safety and Tolerability, Food Effect and Drug-Drug Interaction of LY4268989 (MORF-057) in Healthy Participants

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 27 Oct 2025

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At a glance

  • Drugs MORF 057 (Primary)
  • Indications Crohn's disease; Ulcerative colitis
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Eli Lilly and Company

Most Recent Events

  • 23 Oct 2025 Planned number of patients changed from 66 to 114.
  • 26 Sep 2025 Planned End Date changed from 1 Aug 2025 to 1 Dec 2025.
  • 26 Sep 2025 Planned primary completion date changed from 1 Aug 2025 to 1 Dec 2025.

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