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A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing Olpasiran Use to Prevent First Major Cardiovascular Events in Participants With Elevated Lipoprotein(a)

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Trial Profile

A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing Olpasiran Use to Prevent First Major Cardiovascular Events in Participants With Elevated Lipoprotein(a)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 15 Nov 2025

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At a glance

  • Drugs Olpasiran (Primary)
  • Indications Atherosclerosis; Cardiovascular disorders; Myocardial infarction
  • Focus Registrational; Therapeutic Use
  • Acronyms OCEAN(a)-PreEvent
  • Sponsors Amgen

Most Recent Events

  • 23 Oct 2025 Planned End Date changed from 19 Mar 2031 to 20 Oct 2031.
  • 23 Oct 2025 Planned primary completion date changed from 19 Mar 2031 to 20 Oct 2031.
  • 18 Sep 2025 Planned End Date changed from 18 Oct 2031 to 19 Mar 2031.

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