Trial Profile

A Multicenter, Prospective Phase II Clinical Study of High-Dose Firmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed in the Treatment of EGFR-Mutated Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 20 May 2025

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At a glance

Drugs Bevacizumab (Primary) ; Firmonertinib (Primary) ; Pemetrexed (Primary)
Indications Meningeal carcinomatosis; Non-small cell lung cancer
Focus Therapeutic Use
Acronyms FLAME-1

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