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A Phase III, Multicenter, Open-Label Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Emicizumab Prophylaxis in Patients With Type 3 Von Willebrand Disease

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Trial Profile

A Phase III, Multicenter, Open-Label Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Emicizumab Prophylaxis in Patients With Type 3 Von Willebrand Disease

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 04 Dec 2025

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At a glance

  • Drugs Emicizumab (Primary) ; Factor VIII; Von Willebrand factor
  • Indications Von Willebrand disease
  • Focus Registrational; Therapeutic Use
  • Acronyms WILL-EMI
  • Sponsors Roche

Most Recent Events

  • 16 Oct 2025 Planned number of patients changed from 66 to 75.
  • 16 Oct 2025 Planned primary completion date changed from 15 Dec 2027 to 31 Dec 2026.
  • 04 Jul 2025 Planned End Date changed from 15 May 2029 to 31 Dec 2028.

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