A Phase II, Multicentre, Parallel Group, Open Label, Randomised Clinical Trial of Neoadjuvant Nivolumab and Ipilimumab Combined With Relatlimab for Patients With Resectable Advanced Melanoma Identified as Poor Responders to Immunotherapy
Latest Information Update: 23 Feb 2026
At a glance
- Drugs Ipilimumab (Primary) ; Nivolumab (Primary) ; Relatlimab (Primary) ; Pembrolizumab
- Indications Malignant melanoma; Skin cancer
- Focus Therapeutic Use
- Acronyms Neo IRENIE
Most Recent Events
- 19 Feb 2026 Status changed from not yet recruiting to recruiting.
- 16 Dec 2025 Planned number of patients changed from 531 to 494.
- 16 Dec 2025 Planned End Date changed from 1 Sep 2037 to 1 Jan 2038.