A Phase II, Multicentre, Open Label, Randomised Clinical Trial of Nivolumab and Ipilimumab Combined With Relatlimab for Patients With Resectable Advanced Melanoma Identified as Poor Responders to Immunotherapy
Latest Information Update: 25 Nov 2025
At a glance
- Drugs Ipilimumab (Primary) ; Nivolumab (Primary) ; Relatlimab (Primary)
- Indications Malignant melanoma; Skin cancer
- Focus Therapeutic Use
- Acronyms Neo IRENIE
Most Recent Events
- 19 Nov 2025 The protocol has been amended to addition in treatment arm size.
- 19 Nov 2025 Planned number of patients changed from 297 to 531.
- 19 Nov 2025 Planned primary completion date changed from 1 Sep 2027 to 1 Dec 2027.