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A Proof-of-concept Phase 2a, Double-blind, 2-arm Trial to Investigate the Efficacy and Safety of Twice Daily Delgocitinib Cream 20 mg/g Compared With Cream Vehicle During a 16-week Treatment Period in Adult Subjects With Mild to Severe Palmoplantar Pustulosis

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Trial Profile

A Proof-of-concept Phase 2a, Double-blind, 2-arm Trial to Investigate the Efficacy and Safety of Twice Daily Delgocitinib Cream 20 mg/g Compared With Cream Vehicle During a 16-week Treatment Period in Adult Subjects With Mild to Severe Palmoplantar Pustulosis

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 17 Oct 2025

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At a glance

  • Drugs Delgocitinib (Primary)
  • Indications Palmoplantar pustulosis
  • Focus Proof of concept; Therapeutic Use
  • Acronyms DELTA NEXT

Most Recent Events

  • 29 Aug 2025 Planned initiation date changed from 1 Aug 2025 to 1 Sep 2025.
  • 30 Jul 2025 Planned initiation date changed from 7 Jul 2025 to 1 Aug 2025.
  • 30 Jul 2025 Status changed from not yet recruiting to recruiting.

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