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Efficacy and Safety of Cagrilintide s.c. in Combination With Semaglutide s.c. (CagriSema s.c.) Once Weekly for Weight Management and Long-term Weight Maintenance in Participants With Obesity

Trial Profile

Efficacy and Safety of Cagrilintide s.c. in Combination With Semaglutide s.c. (CagriSema s.c.) Once Weekly for Weight Management and Long-term Weight Maintenance in Participants With Obesity

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 29 Jun 2025

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At a glance

  • Drugs Cagrilintide/semaglutide (Primary)
  • Indications Obesity
  • Focus Registrational; Therapeutic Use
  • Acronyms REDEFINE 11
  • Sponsors Novo Nordisk

Most Recent Events

  • 22 Jun 2025 According to a Novo Nordisk media release, the company initiated the REDEFINE 11 trial with the first patient visit occurring in early June 2025. REDEFINE 11 will explore further weight loss potential and safety of CagriSema 2.4 mg / 2.4 mg through a longer trial duration and other protocol changes compared to REDEFINE 1 and 2. REDEFINE 11 has a longer duration and other protocol changes compared to REDEFINE 1 and 2.
  • 13 Jun 2025 New trial record
  • 11 Jun 2025 Status changed from not yet recruiting to recruiting.

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