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The CAROLYN Trial: Lisocabtagene Maraleucelas First-Line Therapy for Primary Central Nervous System Lymphoma (PCNSL) in Transplant-Ineligible Patients

Trial Profile

The CAROLYN Trial: Lisocabtagene Maraleucelas First-Line Therapy for Primary Central Nervous System Lymphoma (PCNSL) in Transplant-Ineligible Patients

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 12 Jul 2025

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At a glance

  • Drugs Lisocabtagene-maraleucel (Primary) ; Cyclophosphamide; Fludarabine; Folinic acid; Methotrexate; Procarbazine; Rituximab; Temozolomide
  • Indications CNS cancer; Lymphoma
  • Focus Therapeutic Use
  • Acronyms CAROLYN
  • Sponsors Bristol-Myers Squibb; Juno Therapeutics

Most Recent Events

  • 17 Jun 2025 New trial record

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