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Phase 2, Multicenter, Open Label, Platform Study Investigating Tarlatamab (AMG 757) in Patients With Metastatic/Locally Advanced Small-Cell Lung Cancer (SCLC) and Other Poorly Differentiated Neuroendocrine Carcinomas (NECs), With Biomarker Analysis to Characterize Response/Resistance

Trial Profile

Phase 2, Multicenter, Open Label, Platform Study Investigating Tarlatamab (AMG 757) in Patients With Metastatic/Locally Advanced Small-Cell Lung Cancer (SCLC) and Other Poorly Differentiated Neuroendocrine Carcinomas (NECs), With Biomarker Analysis to Characterize Response/Resistance

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 18 Jun 2025

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At a glance

  • Drugs Tarlatamab (Primary)
  • Indications Medullary thyroid cancer; Neuroendocrine carcinoma; Small cell lung cancer
  • Focus Biomarker; Therapeutic Use
  • Acronyms UNLOCK TARLATAMAB

Most Recent Events

  • 18 Jun 2025 New trial record

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