Trial Profile

Phase II Exploratory Study of Sequential Triple Therapy (Temozolomide/Anlotinib/Bemarituzumab) in Combination With Concurrent Radiotherapy With Temozolomide and Anlotinib for the Maintenance Treatment of Diffuse Midline Gliomas in Children

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 18 Jul 2025

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At a glance

Drugs Bemarituzumab (Primary) ; Catequentinib (Primary) ; Temozolomide (Primary)
Indications Glioma
Focus Therapeutic Use

08 Jul 2025 Protocol amended with the replacement of pembrolizumab with bemarituzumab.
08 Jul 2025 Planned initiation date changed from 10 Jun 2025 to 10 Jul 2025.
18 Jun 2025 New trial record

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