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PHOX2B Peptide-Centric Chimeric Antigen Receptor Autologous T cells (PHOX2B PC-CAR T) for Relapsed Neuroblastoma

Trial Profile

PHOX2B Peptide-Centric Chimeric Antigen Receptor Autologous T cells (PHOX2B PC-CAR T) for Relapsed Neuroblastoma

Status: Planning
Phase of Trial: Phase I

Latest Information Update: 20 Jun 2025

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At a glance

  • Drugs PHOX 2B (Primary)
  • Indications Neuroblastoma
  • Focus Adverse reactions; Pharmacokinetics

Most Recent Events

  • 20 Jun 2025 New trial record
  • 12 Jun 2025 According to Myrio Therapeutics media release, This study will be conducted under the leadership of Prof. Maris and it is anticipated that the first patient will be enrolled mid-year 2025.
  • 12 Jun 2025 According to Myrio Therapeutics media release, FDA approved an IND application enabling Myrio's lead product (PHOX2B PC-CAR T) to enter human trials. Myrio, in collaboration the leading children's hospital in Philadelphia have co-developed a Chimeric Antigen Receptor (CAR-T) therapy for the treatment of neuroblastoma.

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