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Iparomlimab/Tuvonralimab Integrating With Total Neoadjuvant Therapy for pMMR/MSS Locally Advanced Rectal Cancer (IT-TNT): A Single-arm, Exploratory, Phase II Trial

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Trial Profile

Iparomlimab/Tuvonralimab Integrating With Total Neoadjuvant Therapy for pMMR/MSS Locally Advanced Rectal Cancer (IT-TNT): A Single-arm, Exploratory, Phase II Trial

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 23 Jun 2025

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At a glance

  • Drugs Capecitabine (Primary) ; Iparomlimab/tuvonralimab (Primary) ; Oxaliplatin (Primary)
  • Indications Adenocarcinoma; Rectal cancer
  • Focus Therapeutic Use
  • Acronyms IT-TNT

Most Recent Events

  • 23 Jun 2025 New trial record

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