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A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMF-650 in Otherwise Healthy Overweight or Obese Participants

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Trial Profile

A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMF-650 in Otherwise Healthy Overweight or Obese Participants

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 19 Jun 2026

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At a glance

  • Drugs BMF 650 (Primary)
  • Indications Obesity
  • Focus Adverse reactions; First in man
  • Sponsors Biomea Fusion

Most Recent Events

  • 06 Jun 2026 Results presented in the Biomea Fusion media release.
  • 09 Apr 2026 Status changed from recruiting to active, no longer recruiting.
  • 12 Jan 2026 According to Biomea Fusion media release, initial 28-day weight loss data from this Phase I study in obese otherwise healthy volunteers are expected in Q2 2026.

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