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A Phase 1, First-in-Human, Open-Label Study to Evaluate the Safety, Tolerability, PK, and Preliminary Anti-tumor Activity of the Novel Oral Selective CDK2/CDK4 Dual Degrader NKT5097 in Adults With Advanced/Metastatic Solid Tumors

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Trial Profile

A Phase 1, First-in-Human, Open-Label Study to Evaluate the Safety, Tolerability, PK, and Preliminary Anti-tumor Activity of the Novel Oral Selective CDK2/CDK4 Dual Degrader NKT5097 in Adults With Advanced/Metastatic Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 25 Jun 2025

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At a glance

  • Drugs NKT-5097 (Primary)
  • Indications Advanced breast cancer; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors NiKang Therapeutics

Most Recent Events

  • 25 Jun 2025 New trial record

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